This Week in Manufacturing - 12/17/2025

Pharma invests in health and jobs, nationwide

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This report is brought to you in partnership with Sustainment, a market network dedicated to the success of American Manufacturing. Learn More →

💴 This Week in Manufacturing

November’s manufacturing data reflected steady production but fragile demand. S&P Global PMI remained in expansion at 52.2, while ISM stayed in contraction at 48.2, with new orders (47.4) and employment (44.0) continuing to weaken under tariff pressure. Record inventory buildups signaled potential future production cuts. Even so, multi-billion-dollar investments from AstraZeneca, Novartis, Toyota, Boeing, First Solar, and Rockwell Automation show that long-term confidence in U.S. manufacturing capacity remains intact despite near-term softness.

This week’s headlines continue that theme of cautious optimism under lingering external pressures from warehouse growth, domestic reshoring, robotics innovations, and more.

Our first podcast, from The Manufacturing Executive, details how focusing on people can bring in profit in a family business. The second podcast, from The Manufacturing Report, showcases an American business repurposing tires into pet toys.

The Social Video and Fun Fact highlight many sides of the pharmaceutical industry from R&D to major growth.

Thanks for joining us!

MONTHLY REPORT

♨️ November 2025 Manufacturing Insights

U.S. manufacturing continued to face headwinds in November 2025, with the sector contracting for the ninth consecutive month according to ISM data, though the competing S&P Global PMI painted a more optimistic picture of sustained expansion.

U.S. manufacturing faced a complex and uneven landscape in November 2025. ISM data showed the sector contracting for a ninth straight month, with weakness in new orders, employment, and supplier deliveries driven largely by tariff-related cost pressures and demand uncertainty. In contrast, S&P Global’s PMI signaled continued expansion, supported by rising output and employment but accompanied by a record inventory buildup that raises concerns about sustainability.

Despite near-term headwinds, companies announced tens of billions of dollars in new U.S. manufacturing investments, underscoring long-term confidence in domestic production capacity.

Upshot: From pharma giants onshoring biologics production to solar manufacturers building AI-enabled facilities, companies are betting on the long-term potential of American manufacturing.

FROM THE FEED

📱The Key Ingredient for Success in R&D

🤨Did You Know?

Pharmaceutical industry has an anticipated compound annual growth rate (CAGR)

5.48% from 2024 to 2030

🎧 Podcasts Worth A Listen

THE MANUFACTURING EXECUTIVE
Scaling a Family Manufacturing Business to $100M with Jenn Barlund

THE MANUFACTURING REPORT
The Portland Startup Saving Millions of Inner Tubes from Landfills